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NICE guidance from 2010 recommends that visual estimation of the severity of neonatal jaundice is no longer used as it is highly inaccurate. The absence of symptoms (i.e. “alert and feeding well”) is not a reliable indicator that treatment is not required either.
Instead whenever neonatal jaundice is seen, the serum bilirubin level should be estimated using transcutaneous bilirubinometry or measured with a blood sample.
This guideline describes the agreed process for the use of transcutaneous bilirubinometers in the community, and should be used in conjunction with the West of Scotland Neonatal MCN Jaundice guideline. Staff using this access should ensure that they have access to the appropriate gestation specific charts (see appendix), and should refer to them with all results.
Jaundice can develop at any time over the first few days of life. All possible opportunities should be used to look for jaundice over this time.
Assess for jaundice at every interaction with a newborn baby in the first days of life. Ensure adequate lighting. Document the absence or presence of jaundice whenever writing a clinical note. In the “colour” section of the daily check in the SWHMR the presence or absence of jaundice should be noted each day.
Particular attention must be paid to the following groups:
Presence of these risk factors should be noted on admission to the ward and it should be ensured that they are regularly assessed for jaundice. NICE recommend that babies with the above factors associated with an increased likelihood of developing significant hyperbilirubinaemia receive an additional visual inspection by a healthcare professional during the first 48 hours of life.
All staff using a transcutaneous bilirubinometer should ensure that they have received adequate training in the use of the device that they have been provided with.
(Except in the following circumstances where serum bilirubins should be measured:
Caution should also be used where there is known or suspected haemolysis (e.g. where there are maternal blood group antibodies of concern, a history of siblings with severe early haemolysis or the baby is DAT positive in keeping with haemolysis). In this group it may be prudent to use serum bilirubin measurements, at least initially. Any baby falling into this group (known or suspected haemolysis) should have their initial management in a hospital setting and a clear plan for follow up sampling etc made by the discharging paediatrician.
Babies over 14 days of age who are visibly jaundiced should follow guidance for prolonged jaundice.
NICE guidance is that for levels up to 250micromol/l transcutaneous measurements are sufficiently accurate to be plotted and acted on without a confirmatory serum bilirubin. Local experience however is less positive than that and so pending further evaluation a “safety margin” will remain in GG&C for more vulnerable infants (less than full term), and for full term infants during the higher risk early days when the bilirubin level is still rising. This margin is that transcutaneous results within 25microl/l of the treatment line should be confirmed with a serum sample. The charts below illustrate this.
A repeat measurement is recommended for those with a level within 50micromol/l of the treatment threshold, as follows:
For all levels, comparison with previous measurements where available is much more informative than looking at a single measurement. This should be borne in mind when using any of these thresholds. Where the rate of rise can be determined it should be used to plan future measurements/samples rather than the action points below. This is particularly relevant on the flatter “plateau” phase of the charts (from 72 or 96 hours of age). If in doubt, please contact the neonatal medical staff/ANNPs for advice.
NICE recommend the following for infants >38 weeks gestation:
For all visibly jaundiced babies (greater than 24 hours, greater than 35 weeks and without previous phototherapy):
|(top line)- treatment threshold (refer)|
|(second line)- refer to hospital|
|(third line)- take SBR|
|(fourth line)- recheck in 18-24 hours|
If previous measurements are available, decisions around the need for SBR sampling/referral to hospital will depend on whether the level is rising or falling, and the age of the child.
Last reviewed: 13 December 2016
Next review: 01 December 2019
Author(s): Dr Allan Jackson – Neonatal Consultant PRM
Co-Author(s): Other Professionals Consulted: Veronica McArthur – Community Midwife PRM
Approved By: GGC Neonatal Guidelines Group